Tenvir EM 200 (200mg/300mg Emtricitabine/Tenofovir)

Product Information

• Strength: Fixed-dose combination tablet

• Class: Antiretroviral (NRTI)

• Form: Oral tablet

• Active ingredients: Emtricitabine and Tenofovir disoproxil fumarate

Why is this Medication Prescribed?

Tenvir EM is prescribed in combination with other antiretroviral medicines for the treatment of HIV infection. It lowers the viral load in the body, supports the immune system, and reduces the risk of HIV-related complications.

It may also be used to prevent HIV infection in high-risk individuals (PrEP, pre-exposure prophylaxis).

Uses

• Treatment of HIV infection

• Prevention of HIV infection in high-risk individuals (PrEP)

Benefits

• Lowers the amount of HIV in the body, slowing progression of the disease

• Helps the immune system work better, reducing infections and complications

• Improves survival and long-term health outcomes when taken regularly

• May prevent HIV infection when used as part of a prevention program

How Should this Medicine be Used?

• Take exactly as prescribed by your doctor

• Best taken with food for optimal absorption

• Take at the same time every day for maximum effectiveness

• Always use in combination with other antiretroviral medicines for HIV treatment

• Do not skip doses — missing doses may reduce effectiveness and increase resistance risk

• Do not stop without your doctor’s advice, even if you feel well

Other Uses

May be prescribed as pre-exposure prophylaxis (PrEP) to reduce HIV infection risk in high-risk populations, under strict medical guidance.

⚠️ HIV Transmission Safety Box

This medicine helps manage HIV infection but does not cure it or prevent the spread of HIV.

• Continue practicing safe sex (use condoms)

• Do not share needles or personal items that may contain blood

• Regular follow-up tests are required to monitor viral load and immune function

🦴 Bone Health Warning

This medicine may reduce bone density and increase your risk of osteoporosis or fractures.

• Your doctor may monitor bone strength and advise calcium/vitamin D supplementation or lifestyle changes

• Regular exercise may help protect bone health

⚠️ Liver Toxicity Warning

This medicine may cause liver damage.

• Your doctor may monitor your liver function with blood tests

• Stop the medicine and seek medical help if you develop:
  • Yellowing of the skin or eyes

  • Dark urine

  • Persistent nausea, vomiting, or abdominal pain

⚠️ Kidney Function Risk Warning

This medicine may cause kidney damage in some patients.

• Your doctor may order regular kidney function tests (creatinine, eGFR)

• Drink enough fluids during treatment unless advised otherwise

• Report to your doctor if you notice:
  • Swelling in feet or ankles

  • Unusual tiredness or weakness

  • Changes in urination (frequency, amount, or pain)

Special Precautions

• Inform your doctor if you have:
  • Kidney disease

  • Liver disease (including hepatitis B or C co-infection)

  • Bone problems such as osteoporosis

  • Skin disorders or history of allergic reactions

• Routine blood tests may be required to monitor kidney function, liver function, and blood counts

• May cause dizziness or sleepiness — avoid driving until you know how it affects you

• Pregnancy & Breastfeeding: Consult your doctor before use

• Do not have unprotected sex or share personal items if you are HIV positive — safe practices are essential to reduce transmission

Possible Side Effects

Common side effects:

• Headache

• Nausea, vomiting

• Diarrhea, flatulence

• Stomach pain

• Rash

• Fatigue

• Insomnia (trouble sleeping)

Rare but serious side effects:

• Severe skin reaction

• Liver damage (jaundice, dark urine, abdominal pain)

• Bone loss (osteoporosis)

• Kidney damage (changes in urination, swelling, weakness)

Storage & Disposal

• Store at room temperature, away from heat, moisture, and sunlight

• Keep out of reach of children

• Do not use after the expiry date

• Dispose of unused tablets safely — do not flush into drains

Emergency Guidance

• Seek urgent medical help if you develop severe allergic reactions (swelling of face, lips, throat, or difficulty breathing)

• Call emergency services if you experience sudden chest pain, severe dizziness, or fainting

• Contact your doctor immediately if you notice signs of liver problems, kidney issues, or unusual bone pain/weakness

• In case of overdose, go to the nearest emergency department immediately