REGESTRONE 5 (5mg norethisterone)

Product Information

REGESTRONE Tablet contains norethisterone, a synthetic version of the natural female sex hormone progesterone. It is used to manage various menstrual problems including heavy or painful periods, irregular periods, premenstrual syndrome (PMS), and endometriosis.

It may be taken with or without food, preferably at the same time each day. Swallow the tablets whole with water. The dose and duration depend on your condition and response to treatment.

Why is this Medication Prescribed?

Doctors prescribe REGESTRONE to:

• Control heavy or painful menstrual bleeding

• Relieve cramps and discomfort during periods

• Manage endometriosis symptoms

• Reduce symptoms of premenstrual syndrome (PMS)

Uses

• Treatment of heavy menstrual bleeding

• Treatment of painful menstruation

• Treatment of endometriosis

• Treatment of premenstrual syndrome (PMS)

Benefits

In Heavy Menstrual Bleeding

• Slows the growth of the womb lining before menstruation

• Reduces the amount of bleeding

• Helps improve daily comfort and quality of life

In Painful Menstruation

• Balances estrogen effects and reduces uterine cramping

• Relieves menstrual pain and discomfort

• May be combined with NSAIDs for rapid relief

In Endometriosis

• Slows abnormal growth of womb-like tissue outside the uterus

• Relieves pelvic pain, period pain, and pain during sex

• Helps improve fertility outcomes in some women

In Premenstrual Syndrome (PMS)

• Reduces mood swings, anxiety, tiredness, and bloating

• Relieves breast tenderness and headaches

• Works best when combined with healthy lifestyle changes

How Should this Medicine be Used?

• Take REGESTRONE exactly as prescribed by your doctor.

• Can be taken with or without food, but at the same time each day.

• Swallow the tablets whole with water.

• Do not stop suddenly unless instructed by your doctor.

• This medicine is usually prescribed for specific days in your menstrual cycle.

Other Uses

May occasionally be used for hormone-related conditions as directed by your doctor.

⚠️ Pregnancy & Birth Defect Risk Warning

This medicine may cause serious harm to an unborn baby, including birth defects or pregnancy loss.

• Do not take this medicine if you are pregnant or planning a pregnancy.

• Stop taking the medicine immediately if you become pregnant and contact your doctor.

• Use effective contraception during treatment.

⚠️ Heart Rhythm / Blood Clot Risk Warning

This medicine may increase the risk of abnormal heart rhythms and blood clots (thrombosis).

• Tell your doctor if you have a history of heart disease, blood clots, stroke, or high blood pressure.

• Stop the medicine and seek urgent care if you experience:
  • Sudden chest pain or shortness of breath

  • Swelling, redness, or pain in the leg

  • Sudden severe headache, vision or speech changes

  • Fainting or palpitations

Special Precautions

• Inform your doctor if you have:
  • Liver disease or history of jaundice

  • Migraine or history of severe headaches

  • Blood circulation problems or history of clots

  • High blood pressure or diabetes

• This medicine may affect blood or urine test results. Inform your healthcare provider before tests.

• Stop treatment if you develop jaundice, migraine, vision or speech changes, or very high blood pressure.

Possible Side Effects

Common:

• Headache or dizziness

• Nausea, vomiting, abdominal cramps

• Vaginal spotting or irregular bleeding

• Breast tenderness

Serious (stop medicine and seek help):

• Jaundice (yellowing of skin or eyes)

• Migraine or severe headache with vision/speech changes

• Sudden chest pain or leg swelling (possible blood clot)

• Very high blood pressure

Storage & Disposal

• Store at room temperature, away from heat and moisture.

• Keep out of reach of children.

• Do not use after the expiry date.

• Dispose of unused tablets safely through pharmacy take-back programs.

Emergency Guidance

• Seek urgent medical help if you experience:
  • Severe allergic reaction (rash, swelling, difficulty breathing)

  • Sudden chest pain, shortness of breath, or leg swelling (possible clot)

  • Severe migraine, vision or speech changes

  • Jaundice (yellow skin/eyes, dark urine)