OFRAMAX Injection (1gm Ceftriaxone)

Product Information

OFRAMAX 1gm Injection is an antibiotic belonging to the cephalosporin group. It is used to treat a wide range of bacterial infections including those of the brain (meningitis), lungs (pneumonia), ear, urinary tract, skin and soft tissues, bones and joints, blood, and heart.

It may also be used to prevent infections during surgery. OFRAMAX is administered as an intravenous infusion (drip) or injected directly into a vein or muscle under the supervision of a healthcare professional.

Your doctor will determine the correct dose and duration of treatment. It is important to receive this medicine at evenly spaced intervals and to complete the full course even if you feel better, as stopping early may lead to the return or worsening of infection.

Why is this Medication Prescribed?

OFRAMAX is prescribed to treat bacterial infections caused by susceptible organisms, and in some cases, to prevent surgical infections.

Uses

• Bacterial meningitis (brain infections)

• Pneumonia and other lung infections

• Ear infections

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

• Bloodstream infections (sepsis)

• Heart infections (endocarditis)

• Prevention of infection during surgery

Benefits

• Broad-spectrum antibiotic effective against many serious bacterial infections

• Helps relieve symptoms within a few days

• Can be used both as treatment and surgical prophylaxis

• Improves recovery and prevents complications of untreated bacterial infections

How Should this Medicine be Used?

• Administered by a healthcare professional as an intravenous infusion or intramuscular injection.

• Given at regular intervals according to your doctor’s prescription.

• Complete the full course as prescribed, even if you feel better.

• Do not skip doses, as this may reduce effectiveness and increase resistance risk.

Other Uses

May be used in other bacterial infections as determined by your doctor.

⚠️ Severe Diarrhea/Colitis Risk Warning
Ceftriaxone may cause serious, potentially life-threatening diarrhea due to Clostridium difficile infection.

• Stop the medicine and contact your doctor immediately if you develop severe, persistent, or bloody diarrhea.

• Do not use anti-diarrheal medicines without medical advice.

• This risk may occur during treatment or even weeks after stopping the medicine.

⚠️ Liver Toxicity Warning
This medicine may cause liver damage or changes in liver function tests. Your doctor may monitor your liver with blood tests.

• Stop taking the medicine and seek medical help if you develop yellowing of the skin or eyes, dark urine, persistent nausea, vomiting, or abdominal pain.

• Avoid alcohol while taking this medicine to reduce liver risk.

Special Precautions

• Inform your doctor if you are allergic to cephalosporins, penicillins, or other antibiotics.

• Tell your doctor if you have kidney or liver problems.

• Let your healthcare provider know about all other medicines you are taking, as interactions may occur.

• Use with caution in newborns and infants, especially those with jaundice or calcium-related issues.

Possible Side Effects

Most side effects are mild and temporary. Contact your doctor if they persist or become severe.

Common side effects:

• Diarrhea

• Rash

• Pain, redness, or swelling at injection site

• Changes in liver function tests

• Changes in blood cell counts

Less common side effects:

• Allergic reactions (rash, itching, swelling, difficulty breathing)

• Severe diarrhea (may indicate colitis)

Storage & Disposal

• Stored by healthcare professionals under appropriate conditions.

• Keep out of reach of children.

• Do not use after the expiry date.

• Proper disposal will be managed by the hospital or clinic.

Emergency Guidance

• Seek urgent medical help if you experience severe allergic reaction (difficulty breathing, swelling of face/throat, widespread rash).

• Report persistent or bloody diarrhea immediately.

• Contact your doctor if you develop jaundice, severe abdominal pain, or unusual bleeding.