COZARTAN H (50mg/12.5mg Losartan/Hydrochlorothiazide)

Product Information

Cozartan H Tablet is a combination of two medicines—Losartan and Hydrochlorothiazide—used to treat high blood pressure (hypertension). Controlling high blood pressure reduces the risk of heart attacks, strokes, and kidney failure.

Losartan relaxes and widens blood vessels, while Hydrochlorothiazide (a “water pill”) increases urine output to lower blood pressure. This dual action provides more effective control when a single medicine alone is insufficient.

The tablet may be taken with or without food. Take it at the same time each day to gain maximum benefit. Continue taking it regularly even if you feel well, as high blood pressure usually has no symptoms. Because Hydrochlorothiazide increases urination, avoid taking this medicine within four hours of bedtime.

Your doctor will determine the correct dose based on your condition and response to treatment. This medicine is not recommended in pregnancy and should be used with caution in people with kidney or liver disease, heart problems, or diabetes. Alcohol may enhance its blood pressure–lowering effects and increase side effects.

Why is this Medication Prescribed?

Cozartan H is prescribed to:

• Control high blood pressure (hypertension)
• Reduce the risk of serious complications such as heart attack, stroke, and kidney damage when blood pressure is controlled

Uses

• Treatment of hypertension (high blood pressure)

Benefits

In Hypertension

• Combines two medicines for stronger blood pressure control.
• Losartan: Relaxes blood vessels and improves blood flow.
• Hydrochlorothiazide: Acts as a diuretic (water pill), increasing urine output to reduce fluid buildup and pressure.
• Helps reduce the long-term risk of heart attack, stroke, and kidney problems.

How Should this Medicine be Used?

• Take exactly as prescribed by your doctor.
• May be taken with or without food.
• Take at the same time daily for best effect.
• Avoid taking it within four hours of bedtime (to reduce nighttime urination).
• Do not stop suddenly unless directed by your doctor.
• Continue lifestyle measures to support blood pressure control:
  • Regular physical activity
  • Reduced salt intake
  • Healthy diet
  • Limiting alcohol
  • Smoking cessation

Other Uses

Your doctor may prescribe Cozartan H for other conditions where combined blood pressure control is needed.

Special Precautions

• Not recommended during pregnancy; may harm the unborn baby.
• Use with caution if breastfeeding (consult your doctor).
• Inform your doctor if you have:
  • Kidney or liver disease
  • Heart conditions
  • Diabetes
  • Gout or a history of high uric acid levels
• Monitoring is important:
  • Blood pressure
  • Kidney function
  • Electrolytes (potassium, sodium, magnesium)
  • Blood sugar (Hydrochlorothiazide may worsen glucose tolerance)
  • Uric acid levels (Hydrochlorothiazide may worsen gout)
• Dizziness may occur—avoid driving or operating machinery until you know how the medicine affects you.
• Avoid excessive alcohol intake as it can worsen side effects.

Possible Side Effects

Most side effects are mild and improve over time. Contact your doctor if persistent or bothersome.

• Nausea
• Taste changes
• Upset stomach
• Diarrhea
• Headache
• Dizziness or weakness
• Low blood pressure
• Increased uric acid (may worsen gout)
• Increased blood lipids (cholesterol, triglycerides)
• Glucose intolerance (may affect blood sugar levels)
• Electrolyte imbalance (low sodium, potassium, or magnesium)

Seek urgent medical help if you develop severe dizziness, fainting, swelling of the face/lips/throat, or difficulty breathing.

Storage & Disposal

• Store in a cool, dry place away from moisture and direct light.
• Keep out of reach of children and pets.
• Do not use after the expiry date printed on the package.
• Dispose of unused tablets safely; do not flush into wastewater.

Emergency Guidance

• Overdose: May cause severe dizziness, fainting, dehydration, or dangerously low blood pressure. Seek emergency medical help.
• Missed dose: Take as soon as remembered. If it is nearly time for the next dose, skip the missed one. Do not double dose.
• Serious reaction: If you experience swelling, difficulty breathing, or chest pain, call emergency services immediately.