Tenvir 300 (300mg Tenofovir disoproxil fumarate)

Product Information

• Strength: 300 mg tablets (commonly available)

• Class: Antiviral (NRTI)

• Form: Oral tablet

• Active ingredient: Tenofovir disoproxil fumarate

Why is this Medication Prescribed?

Tenvir is prescribed in combination with other medicines for the treatment of:

• HIV infection

• Chronic hepatitis B virus (HBV) infection

It helps lower the viral load in the body, slows the progression of disease, and improves quality of life.

Uses

• Treatment of HIV infection (with other antiretroviral drugs)

• Treatment of chronic hepatitis B virus (HBV) infection

• Prevention of HIV infection in high-risk individuals (pre-exposure prophylaxis, PrEP)

Benefits

• Reduces the amount of HIV in the body, lowering the risk of complications and improving survival

• Helps clear hepatitis B virus infection and prevents liver damage

• Can reduce the risk of HIV transmission when used with safe practices (condoms, not sharing needles or personal items)

• Improves long-term health outcomes with regular use

How Should this Medicine be Used?

• Take exactly as prescribed by your doctor

• Best taken with food to improve absorption

• Take at the same time every day for best results

• Always use in combination with other antiretroviral medicines for HIV treatment

• Do not skip doses — missing doses may reduce effectiveness and increase resistance risk

• Do not stop without your doctor’s advice, even if you feel well

Other Uses

Tenofovir may be used in pre-exposure prophylaxis (PrEP) for individuals at high risk of HIV, under strict medical supervision.

⚠️ HIV Transmission Safety Box

This medicine helps manage HIV infection but does not cure it or prevent the spread of HIV.

• Continue practicing safe sex (use condoms)

• Do not share needles or personal items that may contain blood

• Regular follow-up tests are required to monitor viral load and immune function

🦴 Bone Health Warning

This medicine may reduce bone density and increase your risk of osteoporosis or fractures.

• Your doctor may monitor bone strength and advise calcium/vitamin D supplementation or lifestyle changes

• Regular exercise may help protect bone health

⚠️ Liver Toxicity Warning

This medicine may cause liver damage.

• Your doctor may monitor your liver function with blood tests

• Stop the medicine and seek medical help if you develop:
  • Yellowing of the skin or eyes

  • Dark urine

  • Persistent nausea, vomiting, or abdominal pain

⚠️ Kidney Function Risk Warning

This medicine may cause kidney damage in some patients.

• Your doctor may order regular kidney function tests (creatinine, eGFR)

• Drink enough fluids during treatment unless advised otherwise

• Report to your doctor if you notice:
  • Swelling in feet or ankles

  • Unusual tiredness or weakness

  • Changes in urination (frequency, amount, or pain)

Special Precautions

• Tell your doctor if you have:
  • Kidney disease

  • Liver disease (including hepatitis B or C co-infection)

  • Bone problems such as osteoporosis

• Routine blood tests may be required to monitor kidney function, liver function, and blood counts

• May cause dizziness or sleepiness — avoid driving until you know how it affects you

• Pregnancy & Breastfeeding: Consult your doctor before use

• Do not have unprotected sex or share personal items if you are HIV positive — use safe practices to reduce transmission risk

Possible Side Effects

Common side effects:

• Nausea

• Vomiting

• Diarrhea

• Flatulence (gas)

• Rash

• Headache

• Insomnia (difficulty sleeping)

Long-term risks:

• Bone loss (osteoporosis)

• Kidney or liver problems (require monitoring)

Storage & Disposal

• Store at room temperature, away from heat, moisture, and sunlight

• Keep out of reach of children

• Do not use after the expiry date

• Dispose of unused tablets safely — do not flush into drains

Emergency Guidance

• Seek urgent medical care if you develop severe allergic reactions (swelling of face, lips, throat, or difficulty breathing)

• Call emergency services if you experience sudden chest pain, severe dizziness, or fainting

• Contact your doctor immediately if you notice signs of liver problems, kidney issues, or unexplained bone pain/weakness

• In case of overdose, go to the nearest emergency department immediately