Tenvir 300 (300mg Tenofovir disoproxil fumarate)

Oral Antiviral / Nucleotide Reverse Transcriptase Inhibitor (NRTI)

Product Information

Tenvir is prescribed in combination with other medicines for the treatment of:

It helps lower the viral load in the body, slows the progression of disease, and improves quality of life.

Treatment of HIV infection (with other antiretroviral drugs)
Treatment of chronic hepatitis B virus (HBV) infection
Prevention of HIV infection in high-risk individuals (pre-exposure prophylaxis, PrEP)

Reduces the amount of HIV in the body, lowering the risk of complications and improving survival
Helps clear hepatitis B virus infection and prevents liver damage
Can reduce the risk of HIV transmission when used with safe practices (condoms, not sharing needles or personal items)
Improves long-term health outcomes with regular use

Take exactly as prescribed by your doctor
Best taken with food to improve absorption
Take at the same time every day for best results
Always use in combination with other antiretroviral medicines for HIV treatment
Do not skip doses — missing doses may reduce effectiveness and increase resistance risk
Do not stop without your doctor’s advice, even if you feel well

Tenofovir may be used in pre-exposure prophylaxis (PrEP) for individuals at high risk of HIV, under strict medical supervision.

This medicine helps manage HIV infection but does not cure it or prevent the spread of HIV.

This medicine may reduce bone density and increase your risk of osteoporosis or fractures.

Your doctor may monitor bone strength and advise calcium/vitamin D supplementation or lifestyle changes
Regular exercise may help protect bone health

This medicine may cause liver damage.

Your doctor may monitor your liver function with blood tests
Stop the medicine and seek medical help if you develop:
- Yellowing of the skin or eyes
- Dark urine
- Persistent nausea, vomiting, or abdominal pain

This medicine may cause kidney damage in some patients.

Your doctor may order regular kidney function tests (creatinine, eGFR)
Drink enough fluids during treatment unless advised otherwise
Report to your doctor if you notice:
- Swelling in feet or ankles
- Unusual tiredness or weakness
- Changes in urination (frequency, amount, or pain)

Tell your doctor if you have:
- Kidney disease
- Liver disease (including hepatitis B or C co-infection)
- Bone problems such as osteoporosis
Routine blood tests may be required to monitor kidney function, liver function, and blood counts
May cause dizziness or sleepiness — avoid driving until you know how it affects you
Pregnancy & Breastfeeding: Consult your doctor before use
Do not have unprotected sex or share personal items if you are HIV positive — use safe practices to reduce transmission risk

Common side effects:

Long-term risks:

Seek urgent medical care if you develop severe allergic reactions (swelling of face, lips, throat, or difficulty breathing)
Call emergency services if you experience sudden chest pain, severe dizziness, or fainting
Contact your doctor immediately if you notice signs of liver problems, kidney issues, or unexplained bone pain/weakness
In case of overdose, go to the nearest emergency department immediately