SIMLUP 10 (10mg Simvastatin)

Product Information

Simlup 10 Tablet belongs to a group of medicines called statins. It is used to lower cholesterol and reduce the risk of heart disease, heart attack, and stroke. Cholesterol is a fatty substance that can build up in blood vessels, causing narrowing and blockage.

• Usually taken in the evening, with or without food.

• Taking it with food may reduce nausea.

• Should be taken regularly for best results.

• Most people with high cholesterol feel well, but stopping the medicine can worsen cholesterol levels and increase the risk of heart disease or stroke.

• Regular cholesterol checks are necessary.

• Treatment should include diet, exercise, weight control, smoking cessation, and limited alcohol intake.

Why is this Medication Prescribed?

Simlup is prescribed to:

• Lower cholesterol (LDL) and triglycerides

• Increase good cholesterol (HDL)

• Reduce the risk of cardiovascular disease, heart attack, and stroke

Uses

• High cholesterol

• Prevention of heart attack and stroke

Benefits

• High cholesterol: Lowers LDL (“bad” cholesterol) and raises HDL (“good” cholesterol), reducing long-term risks of atherosclerosis and heart disease.

• Prevention of heart attack and stroke: Prevents narrowing of blood vessels, reducing cardiovascular risk.

How Should this Medicine be Used?

• Take once daily in the evening.

• Can be taken with or without food.

• Continue treatment even if you feel well.

• Follow a healthy diet and lifestyle to maximize effectiveness.

Other Uses

None beyond those specified.

⚠️ Liver Toxicity Warning

This medicine may cause liver damage. Your doctor may monitor your liver function with blood tests.

• Stop taking and seek medical help if you develop yellowing of the skin or eyes, dark urine, persistent nausea, vomiting, or abdominal pain.

• Avoid alcohol to reduce liver risk.

⚠️ Muscle Damage Risk Warning

This medicine may rarely cause serious muscle problems, including rhabdomyolysis (muscle breakdown).

• Report unexplained muscle pain, tenderness, or weakness immediately, especially if accompanied by fever or dark urine.

• Risk is higher if combined with certain medicines (e.g., some antibiotics, antifungals, or other cholesterol-lowering drugs).

🍷 Alcohol Warning

Avoid drinking alcohol while taking this medicine.

• Alcohol increases the risk of liver damage and may worsen muscle side effects.

• Limit or avoid alcohol consumption to reduce complications.

⚠️ Heart Rhythm Risk Warning

This medicine may cause abnormal heart rhythms (QT prolongation), especially when taken with other medicines that affect heart rhythm.

• Tell your doctor if you have heart disease, low potassium or magnesium, or a family history of sudden cardiac death.

• Report palpitations, fainting, or dizziness immediately.

Special Precautions

Before taking Simlup, inform your doctor if you have:

• Liver disease

• Kidney problems

• Diabetes (may increase blood sugar levels)

• History of muscle disorders

• Excessive alcohol intake

• Heart rhythm problems or electrolyte imbalance

Pregnancy & Breastfeeding:

• Do not use during pregnancy — may harm the baby.

• Do not use while breastfeeding.

Possible Side Effects

Common side effects include:

• Headache

• Abdominal pain

• Constipation

• Nausea

• Upper respiratory infections

Serious side effects (seek medical attention):

• Yellowing of eyes or skin (possible liver issues)

• Repeated or unexplained muscle pain or weakness

• Severe fatigue or dark urine

• Palpitations, fainting, or dizziness

Storage & Disposal

• Store at room temperature, away from moisture and heat.

• Keep out of reach of children.

• Do not use after expiry date.

• Dispose of unused tablets safely through a pharmacy take-back program.

Emergency Guidance

Seek emergency medical help if you experience:

• Severe muscle pain with weakness and dark urine

• Signs of liver injury (jaundice, abdominal pain, dark urine)

• Severe allergic reaction (swelling, difficulty breathing, rash)

Palpitations, fainting, or abnormal heartbeat